Definition of "Lose" :

verb: be set at a disadvantage

"The painting loses something in this light."

verb: withdraw, as from reality

verb: fail to win

verb: suffer the loss of a person through death or removal

verb: fail to perceive or to catch with the senses or the mind

verb: allow to go out of sight or mind

"Lose the crowds by climbing a mountain."

verb: miss from one's possessions; lose sight of

verb: fail to keep or to maintain; cease to have, either physically or in an abstract sense

verb: fail to get or obtain

verb: fail to make money in a business; make a loss or fail to profit