Synonyms For "Nettlesome" :
2 syllables:
cranky, fractious, galling, peckish, peevish, pesky, pettish, plaguey, plaguy, scratchy, teasing, techy, testy, tetchy, vexing
3 syllables:
annoying, bothersome, pestering, petulant, vexatious
4 syllables:
irritable, irritating, pestiferous